建筑工业化发展的多群体演化博弈与仿真研究

新型建筑工业化具有高质量、低消耗、可循环发展等特征，其推广已上升到国家战略层面。利用演化博弈方法，建立“政府-开发商-银行” 的三方动态演化博弈模型，进行各博弈主体策略的演化稳定性分析，并针对初始状态、奖惩力度、借贷风险和开发成本等对演化结果的影响进行动态仿真。在此基础上， 考虑开发商群体的网络拓扑特征对演化真实性的影响，引入复杂网络理论， 以无标度网络为载体描述开发商个体的连接偏好和决策机制，构建政府监管下的建筑工业化扩散模型，并通过仿真深入研究相关因素对扩散深度的影响作用，最后结合仿真结果给出相应对策建议。     

油田地面建设工程项目进度与管理探讨

油田地面工程项目投资大,质量要求严格,因此工程项目进度控制与项目管理难度很大。本文主要分析油田地面工程项目进度控制与项目管理的影响因素,并有针对性的提出优化措施,希望能提升油田地面工程项目建设水平。     

重复采动覆岩裂隙率空间分布相似模拟研究——以陕北矿区为例

由于水资源短缺,陕北矿区利用采空区储存矿井水进行再利用,采空区储水量与采动裂隙空间分布密切相关,为准确预测采空区储水量,基于工作面上覆岩层断裂分带划分结果,确定煤矿地下水库的主要储水空间为垮落带与断裂带的裂隙空间,建立了采动覆岩裂隙率空间分布的计算方法,采用相似模拟试验得出了柠条塔矿1^-2煤和2^-2煤重复采动后上覆岩层的下沉曲线,计算出重复采动覆岩裂隙率在垂直和水平方向的空间分布情况。结果表明:沿垂直方向,随着高度增加,覆岩裂隙率逐渐减小,1^-2煤开采后岩层裂隙率由1.87%逐渐下降为1.18%,2^-2煤开采后,裂隙率由12.85%下降为4.11%;沿水平方向,垮落带、断裂带和弯曲下沉带的裂隙率在采空区边缘附近都会产生2个峰值,并且峰值位置逐渐向采空区中央移动,1^-2煤开采后,中间压实区的最大裂隙率为1.21%,两边离层区的最大裂隙率为2.19%,2^-2煤开采后,压实区和离层区最大裂隙率分别为16.1%和6.54%;重复开采后,上覆岩层的裂隙率显著增加,有...     

剪切解络-超滤分离金属关键指标预测与验证

根据剪切解络-超滤过程中金属离子的动态浓度关系和质量守恒定律,采用CodeBlocks17.12软件编写程序,建立了剪切解络-超滤工艺关键指标预测模型,实现了金属离子浓度、回收率、体积稀释倍数等指标的预测,并用实验加以验证。依次在转速800 r/min、1 400 r/min、3 000 r/min下回收模拟废水中43 μg/L的Co²⁺、995 μg/L的Ni²⁺和88 μg/L的La³⁺,3种金属的回收率均达99.8%以上时,超滤过程体积稀释倍数的预测值分别为7.0、7.5、5.75,实验值分别为7.5、7.25、6.25,可见预测值与实验值基本一致。本模型对研究方案制定和调整有实际指导意义。     

CD34⁺ CD38^- subpopulation without CD123 and CD44 is responsible for LSC and correlated with imbalance of immune cell subsets in AML

Acute myeloid leukemia (AML) is regarded as a stem cell disease. However, no one unique marker is expressed on leukemia stem cells (LSC) but not on leukemic blasts nor normal hematopoietic stem cells (HSC). CD34⁺ CD38- with or without CD123 or CD44 subpopulations are immunophenotypically defined as putative LSC fractions in AML. Nevertheless, markers that can be effectively and simply held responsible for the intrinsical heterogeneity of LSC is still unclear. In the present study, we examined the frequency of three different LSC subtypes (CD34⁺ CD38^-, CD34⁺ CD38^- CD123⁺ , CD34⁺ CD38^- CD44⁺ ) in AML at diagnosis. We then validated their prognostic significance on the relevance of spectral features for diagnostic stratification, immune status, induction therapy response, treatment effect maintenance, and long-term survival. In our findings, high proportions of the above three different LSC subtypes were all significantly characterized with low complete remission (CR) rate, high relapse/refractory rate, poor overall survival (OS), frequent FLT3-ITD mutation, the high level of regulatory T cells (Treg) and monocytic myeloid-derived suppressor cells (M-MDSC). However, there was no significant statistical difference in all kinds of other clinical performance among the three different LSC groups. It was demonstrated that CD34⁺ CD38^- subpopulation without CD123 and CD44 might be held responsible for LSC and correlated with an imbalance of immune cell subsets in AML.